
Ozempic, Wegovy, and Mounjaro for Phoenix Residents
GLP-1 receptor agonists are FDA-approved medications that mimic hormones naturally produced in your intestines to regulate blood sugar and appetite, leading to significant weight loss. Recent clinical trials show patients lose 15-20% of their body weight within the first year of treatment. For Phoenix residents struggling with obesity and type 2 diabetes, GLP-1 medications like Ozempic, Wegovy, and Mounjaro offer a non-surgical path to substantial weight reduction and improved metabolic health. Dr. Maria R. Brown’s Valley Bariatric practice provides comprehensive medical weight loss programs featuring these breakthrough medications, with personalized dosing protocols designed for Arizona’s unique climate considerations.
Table of Contents
- Understanding GLP-1 Medications
- Ozempic vs Wegovy vs Mounjaro: Complete Comparison
- Expected Weight Loss Results with GLP-1 Medications
- Choosing the Right Provider: Critical Safety Considerations
- Dosing Protocols and Administration
- Side Effects and Management Strategies
- Compounding Pharmacies: Benefits and Controversies
- Dr. Brown’s Medical Weight Loss Program
- Patient Success Stories from Phoenix
- Frequently Asked Questions
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The Weight Loss Medication Dilemma Facing Phoenix Residents
Despite Arizona having one of the highest obesity rates in the Southwest at over 32%, traditional diet and exercise approaches fail for 95% of people attempting significant weight loss. Phoenix residents face additional challenges including extreme heat limiting outdoor exercise for 4-5 months annually, cultural food traditions, and limited access to specialized obesity medicine.
The consequences extend far beyond appearance. Obesity-related conditions affect too many Phoenix-area adults with the following ailments:
- Type 2 diabetes (affecting 1 in 4 Arizona adults)
- High blood pressure (contributing to Arizona’s 15% higher cardiovascular death rate)
- Sleep apnea (exacerbated by desert heat and air quality)
- Joint problems (worsened by concrete surfaces and limited low-impact exercise options)
The emotional toll compounds daily. Patients describe feeling trapped, watching their health deteriorate while facing judgment from healthcare providers who suggest “just eat less and move more” – advice that ignores the complex hormonal and metabolic factors driving obesity.
GLP-1 receptor agonists represent the most significant breakthrough in obesity medicine in decades, offering Phoenix residents a scientifically-proven path to sustainable weight loss without surgery.
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What Are GLP-1 Medications?
GLP-1 (glucagon-like peptide-1) receptor agonists are medications that mimic hormones naturally produced in your small intestine. They slow gastric emptying, increase insulin sensitivity, and directly signal your brain to reduce appetite and food cravings.
Understanding GLP-1 Medications
GLP-1 medications work by targeting the root biological mechanisms that drive obesity and metabolic dysfunction. Unlike stimulant-based appetite suppressants that create jittery side effects, GLP-1 drugs work with your body’s natural hormone systems.
How GLP-1 Medications Transform Weight Loss
These medications address obesity at the hormonal level by:
Appetite Regulation: GLP-1 receptors in your brain’s hypothalamus receive stronger satiety signals, naturally reducing portion sizes without willpower battles.
Gastric Emptying: Food stays in your stomach longer, creating prolonged fullness that eliminates between-meal cravings.
Blood Sugar Control: Enhanced insulin sensitivity prevents the blood sugar spikes and crashes that trigger hunger and food cravings.
Metabolic Enhancement: Improved fat oxidation helps your body burn stored fat more efficiently, particularly beneficial in Phoenix’s sedentary-inducing heat.
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Ozempic vs Wegovy vs Mounjaro: Complete Comparison
| Medication | Active Ingredient | FDA Approval | Average Weight Loss | Starting Dose | Maximum Dose | Key Benefits |
|---|---|---|---|---|---|---|
| Ozempic | Semaglutide | Type 2 Diabetes (2017) | 12-15% body weight | 0.25mg weekly | 2.0mg weekly | Excellent diabetes control, cardiovascular benefits |
| Wegovy | Semaglutide | Obesity (2021) | 14.9% body weight | 0.25mg weekly | 2.4mg weekly | FDA-approved for obesity, heart health benefits |
| Mounjaro | Tirzepatide | Type 2 Diabetes (2022) | Up to 22.5% body weight | 2.5mg weekly | 15mg weekly | Superior weight loss, dual hormone action |
Ozempic: The Diabetes-First Approach
Originally developed for type 2 diabetes management, Ozempic provides excellent glycemic control while delivering significant weight loss as a secondary benefit. Phoenix patients with pre-diabetes or metabolic syndrome often see dramatic improvements in their glucose tolerance tests within 12 weeks.
Best For: Patients with type 2 diabetes or pre-diabetes seeking combined glucose control and weight loss.
Wegovy: Purpose-Built for Weight Loss
Wegovy uses the same semaglutide molecule as Ozempic but at higher therapeutic doses specifically FDA-approved for chronic weight management. Clinical trials demonstrate average significant weight loss through continued use over a year.
Best For: Patients focused primarily on weight loss with BMI ≥30 or BMI ≥27 with weight-related health conditions.
Mounjaro: The Dual-Action Powerhouse
Tirzepatide represents next-generation obesity pharmacotherapy, targeting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual mechanism produces superior weight loss outcomes compared to single-action medications.
Best For: Patients seeking maximum weight loss potential, particularly those who haven’t achieved goals with other GLP-1 medications.
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Expected Weight Loss Results with GLP-1 Medications
Understanding realistic weight loss expectations with GLP-1 medications helps Phoenix residents make informed decisions about their treatment path. Clinical trial data and real-world outcomes provide clear benchmarks for success.
Clinical Trial Results by Medication
Semaglutide (Ozempic/Wegovy) – STEP Trial Results:
- Average Total Body Weight Loss: 14.9% at 68 weeks
- Patients Losing ≥5% Body Weight: 86% (vs 32% placebo)
- Patients Losing ≥10% Body Weight: 69-75%
- Timeline to Peak Weight Loss: 60-68 weeks
Tirzepatide (Mounjaro) – SURMOUNT Trial Results:
- Average Total Body Weight Loss: Up to 22.5% at 72 weeks (15mg dose)
- Patients Losing ≥10% Body Weight: 78-84% (10-15mg doses)
- Patients Losing ≥20% Body Weight: 50-57% (10-15mg doses)
- Timeline to Peak Weight Loss: 72 weeks
Real-World Weight Loss Expectations
Weight Loss Timeline for Phoenix Patients:
Month 1-3: 3-8% body weight loss, appetite suppression begins
Month 4-6: 8-12% body weight loss, metabolic improvements visible
Month 7-12: 12-18% body weight loss, plateau phase common
Month 13-18: 15-22% total weight loss, maintenance phase begins
Factors Affecting Individual Results
Enhanced Results Factors:
- Starting BMI over 35 (greater absolute weight loss potential)
- Adherence to lifestyle modifications (diet and exercise)
- Optimal medication dosing without significant side effects
- Treatment of underlying insulin resistance
- Adequate sleep and stress management
Reduced Results Factors:
- Previous weight loss surgery (altered gut hormone response)
- Certain medications (steroids, antipsychotics, insulin)
- Untreated thyroid disorders or hormonal imbalances
- Significant muscle loss during weight reduction
- Poor medication adherence or frequent dose interruptions
Comparing Medical vs. Surgical Weight Loss
The decision between GLP-1 medications and bariatric surgery depends on individual circumstances, health status, and weight loss goals.
Use our interactive calculator to compare expected outcomes: Weight Loss Calculator: Medical vs. Surgical Options
This tool provides personalized projections based on your current weight, health conditions, and treatment preferences, helping you understand potential outcomes with both medical management and surgical options.
Maintaining Weight Loss Long-Term
Success Strategies for Phoenix Residents:
- Continued medication therapy (most patients regain weight if discontinued)
- Regular monitoring with healthcare providers every 3-4 months
- Adaptation of lifestyle habits to desert climate challenges
- Building sustainable exercise routines for year-round consistency
- Nutritional support to prevent muscle loss during weight reduction
Common Plateau Management:
- Medication dose optimization or switching between GLP-1 agents
- Addition of complementary weight loss medications
- Intensification of lifestyle interventions
- Evaluation for underlying metabolic barriers
- Consideration of surgical options for maximum weight loss
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Choosing the Right Provider: Critical Safety Considerations
The GLP-1 “Gold Rush” – Buyer Beware
The explosive popularity of GLP-1 medications has created an unfortunate phenomenon across Phoenix: a “dash for cash” among healthcare providers who lack proper training in obesity medicine. Just last month, a handwritten sign appeared at the McQueen and 202 freeway stoplight advertising “Ozempic prescriptions” – a stark reminder that not everyone offering these medications has the expertise to manage them safely.
While many healthcare providers can legally prescribe GLP-1 medications, having a prescription pad doesn’t equate to having the specialized knowledge needed for safe, effective weight loss management. The difference between proper medical supervision and casual prescribing can mean the difference between successful weight loss and serious complications.
Red Flags: Warning Signs of Inexperienced Providers
Immediate Red Flags:
- Handwritten roadside signs or crude advertising
- “Quick start” same-day prescriptions without comprehensive evaluation
- Providers who don’t require baseline laboratory work
- Offers to prescribe without seeing medical records or previous weight loss attempts
- Focus solely on medication without lifestyle counseling
- Unwillingness to discuss potential side effects or contraindications
- No follow-up appointment scheduling for monitoring
Concerning Business Practices:
- Pressure to purchase multiple months of medication upfront
- No medical facility address or only mobile/pop-up locations
- Providers operating outside their specialty scope (dermatologists, gynecologists, plastic surgeons offering weight loss as a side business)
- No emergency contact information or after-hours support
What to Look for in a Qualified GLP-1 Provider
Essential Credentials and Training:
- Board certification in obesity medicine, endocrinology, internal medicine, or bariatric surgery
- Fellowship training or certification in weight management
- Active membership in professional organizations (ASMBS, TOS, AACE)
- Hospital privileges and established medical practice location
- Malpractice insurance and state medical board good standing
Comprehensive Care Standards:
- Detailed medical history and physical examination before prescribing
- Baseline laboratory testing (CBC, CMP, lipid panel, HbA1c, thyroid function)
- Review of contraindications and medication interactions
- Documented weight loss history and previous treatment attempts
- Psychological evaluation for eating disorders or contraindications
Ongoing Medical Management:
- Structured follow-up appointments (monthly initially, then quarterly)
- Regular laboratory monitoring for safety parameters
- Documented dose escalation protocols based on tolerance and efficacy
- Side effect management protocols and emergency procedures
- Coordination with other healthcare providers (endocrinologist, cardiologist)
Questions to Ask Potential Providers
About Their Experience:
- “How many GLP-1 patients do you currently manage?”
- “What is your training background in obesity medicine?”
- “How do you handle serious side effects like pancreatitis or gallbladder issues?”
- “What percentage of your patients achieve their weight loss goals?”
- “Do you provide 24/7 emergency support for medication-related issues?”
About Their Practice Standards:
- “What baseline testing do you require before starting medication?”
- “How often will you monitor my laboratory values and vital signs?”
- “What is your protocol for dose adjustments and side effect management?”
- “Do you coordinate with my other doctors (endocrinologist, cardiologist)?”
- “What happens if I need to discontinue the medication?”
About Their Comprehensive Approach:
- “Do you provide nutritional counseling and lifestyle support?”
- “How do you address psychological factors affecting weight loss?”
- “What other weight loss treatments do you offer if GLP-1 medications don’t work?”
- “Do you work with insurance companies for prior authorizations?”
- “What is your long-term maintenance plan for sustained weight loss?”
Phoenix-Specific Provider Evaluation
Established Medical Practices to Consider:
- Providers affiliated with major health systems
- Board-certified bariatric surgeons who offer medical weight loss
- Endocrinologists with obesity medicine training
- Internal medicine physicians with weight management certification
Warning Signs Specific to Phoenix Market:
- Providers advertising heavily on social media with before/after photos
- “Medical spas” or cosmetic practices adding weight loss as a service
- Mobile providers operating from different locations each day
- Practitioners without established Arizona medical licenses
The Importance of Specialized Expertise
Why Expertise Matters:
GLP-1 medications aren’t simply appetite suppressants – they’re powerful hormonal therapies that affect multiple body systems. Proper management requires understanding of:
- Complex drug interactions with diabetes medications
- Recognition and treatment of serious side effects
- Appropriate patient selection and contraindication screening
- Integration with comprehensive lifestyle interventions
- Long-term maintenance strategies and plateau management
Consequences of Inadequate Care:
- Dangerous hypoglycemic episodes from improper dosing
- Unrecognized pancreatitis or gallbladder complications
- Medication discontinuation due to preventable side effects
- Failure to achieve weight loss goals due to poor management
- Development of eating disorders or psychological complications
Valley Bariatric’s Comprehensive Approach
Dr. Brown’s practice exemplifies the gold standard for GLP-1 management, offering:
- Board certification in general surgery with bariatric fellowship training
- Comprehensive team including registered dietitians, psychologists, and exercise programs
- 24/7 emergency support for medication-related complications
- Coordination with other specialists
- Evidence-based protocols following ASMBS and TOS guidelines
Patient Safety First:
Every Valley Bariatric patient receives the same thorough evaluation and ongoing monitoring that Dr. Brown provides for her surgical patients, ensuring the highest standards of safety and efficacy in medical weight loss management.
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Dosing Protocols and Administration
Phoenix-Specific Dosing Considerations
Arizona’s extreme heat and low humidity create unique metabolic challenges requiring modified dosing approaches:
Summer Months (May-September):
- Slower dose escalation to prevent dehydration-related nausea
- Increased emphasis on electrolyte monitoring
- Modified injection timing to avoid peak heat hours
Winter Months (October-April):
- Standard dose escalation protocols
- Opportunity for more aggressive lifestyle interventions
Injection Technique and Storage
Proper Storage in Phoenix Heat:
- Refrigerate between 36-46°F (never freeze)
- Use insulated travel cases during summer months
- Rotate injection sites weekly (abdomen, thigh, upper arm)
- Inject at same time weekly for consistent blood levels
Individualized Dose Escalation Strategy
Patient-Centered Approach: GLP-1 medications are not “one-size-fits-all” treatments. Dr. Brown’s approach focuses on finding each patient’s optimal therapeutic dose through careful, individualized escalation based on how your body responds to treatment.
The Gradual Escalation Process:
Initial Starting Phase: All patients begin with the lowest possible therapeutic dose to minimize side effects while allowing the body to adjust to the medication’s effects. This starting dose is typically well-tolerated and allows healthcare providers to assess initial response.
Response-Based Increases: Every 4 weeks, Dr. Brown evaluates multiple factors to determine if dose adjustment is appropriate:
- Weight loss progress toward goals
- Side effect tolerance and severity
- Appetite suppression effectiveness
- Overall patient comfort and quality of life
- Laboratory values and safety parameters
Factors Influencing Dose Adjustments:
Positive Response Indicators (may support dose increase):
- Minimal to no side effects at current dose
- Continued appetite and food cravings
- Weight loss plateau after 6-8 weeks at current dose
- Patient reports feeling comfortable with current dose
- Normal laboratory values and vital signs
Caution Indicators (may warrant staying at current dose):
- Persistent nausea or gastrointestinal side effects
- Achieving steady weight loss at current dose
- Patient preference to maintain current level
- Any concerning laboratory changes
- Difficulty with medication adherence
Maximum Tolerance Approach: Rather than pushing every patient to the highest available dose, Valley Bariatric focuses on finding each individual’s “sweet spot” – the dose that provides optimal weight loss with minimal side effects. Some patients achieve excellent results at lower doses, while others may benefit from higher therapeutic levels.
Phoenix-Specific Dosing Modifications:
Heat-Related Adjustments: During extreme heat periods (temperatures above 110°F), dose escalations may be delayed to prevent dehydration-related complications. Phoenix patients often require additional electrolyte monitoring during summer months.
Seasonal Considerations: Many Phoenix patients find dose increases easier to tolerate during cooler months (October-April) when heat-related nausea is less problematic. Dr. Brown may time major dose escalations to coincide with more comfortable weather patterns.
Lifestyle Integration: Dose timing and escalation schedules are adjusted based on individual lifestyle factors, including work schedules, travel patterns, and seasonal activity levels common in the Phoenix area.
Safety Monitoring Throughout Escalation:
Regular Assessment Points:
- Weekly check-ins during first month
- Bi-weekly monitoring during dose escalation phases
- Monthly comprehensive evaluations once stable dose achieved
- Laboratory monitoring every 3 months or as clinically indicated
Red Flag Monitoring: Dr. Brown’s team is specially trained to recognize early warning signs that may require dose reduction or medication discontinuation, ensuring patient safety throughout the escalation process.
Patient Education and Empowerment: Patients receive detailed education about what to expect at each dose level, how to recognize concerning symptoms, and when to contact the medical team. This collaborative approach ensures patients feel confident and supported throughout their dose optimization journey.
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Side Effects and Management Strategies
Common Side Effects and Phoenix-Specific Management
Gastrointestinal Effects (60-80% of patients):
Nausea and Vomiting:
- Most common during first 8-12 weeks
- Phoenix management: Increase fluid intake, avoid spicy Southwest cuisine initially
- Timing strategy: Inject before bedtime to sleep through peak nausea
Constipation:
- Affects 30-40% of patients
- Arizona-specific solutions: Increase fiber gradually, maintain hydration despite dry climate
- Recommended: 25-30g fiber daily, 80-100oz water in summer months
Metabolic Adaptations:
Hypoglycemia Risk:
- Higher risk when combined with other diabetes medications
- Phoenix heat can mask hypoglycemia symptoms
- Monitor blood glucose more frequently during summer months
Serious Side Effects Requiring Medical Attention
Pancreatitis Warning Signs:
- Severe abdominal pain radiating to back
- Nausea with inability to keep fluids down
- Fever above 101°F
Thyroid Considerations:
- Family history of medullary thyroid carcinoma (contraindication)
- Multiple endocrine neoplasia syndrome type 2 (contraindication)
- Regular monitoring for patients with thyroid nodules
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Compounding Pharmacies: Benefits and Controversies
Understanding Compounded GLP-1 Medications
The unprecedented demand for GLP-1 medications has created significant supply shortages, leading many Phoenix patients to explore compounded alternatives. Compounding pharmacies create customized versions of these medications, often at substantially lower costs.
Important Disclosure:
Compounded medications are not FDA-approved and may vary in potency, purity, and effectiveness compared to brand-name drugs. Always discuss compounding options with a qualified healthcare provider.
Benefits of Compounded GLP-1 Medications
Cost Accessibility:
- Significant cost reduction compared to brand medications
- Cash-pay options for uninsured Phoenix residents
- Flexible dosing options not available in commercial products
Customization Opportunities:
- Adjusted concentrations for sensitive patients
- Combination formulations (B12, MIC injections)
- Alternative delivery methods (sublingual, nasal)
Controversies and Concerns
Patent Infringement Issues:
Pharmaceutical companies argue that compounding patented medications during shortages represents intellectual property violation. Legal challenges are ongoing, with potential implications for continued availability.
Quality Control Variability:
- FDA doesn’t regulate compounding pharmacies as strictly as manufacturers
- Potency variations of 10-15% common between batches
- Limited stability data for long-term storage
Regulatory Uncertainty:
If FDA declares shortages resolved, compounding pharmacies may be required to stop producing GLP-1 medications, leaving patients without affordable access.
Dr. Brown’s Approach to Compounded Medications
Dr. Brown works exclusively with USP 797-compliant compounding pharmacies that provide:
- Third-party potency testing for every batch
- Sterile preparation protocols exceeding FDA standards
- Full ingredient transparency and sourcing documentation
- Patient education about risks and benefits
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Dr. Brown’s Medical Weight Loss Program
Comprehensive Care Beyond Medication
Dr. Maria R. Brown’s Valley Bariatric practice offers Arizona’s most comprehensive medical weight loss program, combining GLP-1 medications with evidence-based lifestyle interventions tailored for desert living.
Program Components
Initial Assessment:
- Complete metabolic panel including insulin resistance markers
- Body composition analysis
- Nutritional assessment with registered dietitian
- Exercise programs adapted for Phoenix climate
- Psychological evaluation for eating behaviors
Medication Management:
- Personalized GLP-1 selection based on medical history and goals
- Dose optimization protocols
- Side effect management strategies
- Insurance navigation and prior authorization assistance
Lifestyle Integration:
- Phoenix-specific nutrition planning (hydration strategies, seasonal eating)
- Exercise protocols adapted for extreme heat (indoor alternatives, early morning scheduling)
- Stress management techniques for urban desert lifestyle
- Sleep optimization despite temperature fluctuations
Treatment Options and Personalization
Option 1: Surgical Candidacy Assessment
For patients with BMI ≥40 or BMI ≥35 with comorbidities, Dr. Brown provides comprehensive evaluation for bariatric surgery options including gastric sleeve, gastric bypass, and duodenal switch procedures.
Option 2: Medical Weight Loss Focus
Patients preferring non-surgical approaches receive intensive medical management with GLP-1 medications, appetite suppressants, and metabolic support therapies.
Option 3: Hybrid Approach
Some patients benefit from pre-surgical weight loss with GLP-1 medications to reduce surgical risks, followed by bariatric surgery for maximum long-term success.
Success Metrics and Monitoring
Ongoing Assessments Include:
- Weight and body composition tracking
- Blood pressure and heart rate monitoring
- Laboratory panels (comprehensive metabolic panel, HbA1c, lipid profile)
- Medication tolerance and efficacy evaluation
- Lifestyle adherence and barrier identification
Comprehensive Reviews:
- Body composition analysis and comparisons
- Cardiovascular risk assessment
- Nutritional status evaluation
- Exercise capacity testing
- Psychological wellness screening
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Frequently Asked Questions
Q: How long do I need to take GLP-1 medications?
A: Current evidence suggests GLP-1 medications work best as long-term therapy. Most patients regain weight within 6-12 months of discontinuation. Think of these medications like blood pressure or cholesterol medications – chronic conditions requiring ongoing management.
Q: Can I take GLP-1 medications if I’m planning bariatric surgery?
A: Yes, many patients use GLP-1 medications for pre-surgical weight loss to reduce operative risks. Dr. Brown often recommends 3-6 months of medical weight loss before surgical evaluation to optimize outcomes.
Q: Are compounded GLP-1 medications safe?
A: When obtained from reputable, USP 797-compliant pharmacies, compounded GLP-1 medications can be safe and effective. However, they’re not FDA-approved and may have variability in potency. Dr. Brown only works with verified compounding pharmacies that provide batch testing results.
Q: What happens if I can’t tolerate the side effects?
A: Side effect management is a crucial part of treatment success. Options include slower dose escalation, medication timing adjustments, dietary modifications, and switching between different GLP-1 medications. Very few patients need to completely discontinue therapy.
Q: How do GLP-1 medications compare to bariatric surgery for weight loss?
A: Bariatric surgery typically produces greater weight loss (60-80% excess weight loss vs 15-25% total weight loss with medications). However, medications offer reversibility, lower risk profiles, and may be preferred for patients with lower BMIs or those wanting to avoid surgery.
Q: Do I need to follow a special diet while taking GLP-1 medications?
A: While no specific diet is required, patients typically find success with higher protein, lower refined carbohydrate approaches. Valley Bariatric’s registered dietitians provide Phoenix-specific meal planning that accounts for local food culture and seasonal availability.
Q: How do I know if my provider is qualified to prescribe GLP-1 medications?
A: Look for board certification in obesity medicine, endocrinology, or bariatric surgery, comprehensive evaluation before prescribing, regular monitoring protocols, and established practice locations. Avoid providers with handwritten signs, same-day prescriptions without evaluation, or cash-only operations.
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Take Action: Take Your Last First Step Today
Don’t let another Phoenix summer pass feeling uncomfortable in your own body. Dr. Maria R. Brown’s comprehensive medical weight loss program offers the expertise, support, and cutting-edge treatments you need to achieve lasting results.
Ready to explore your options?
Schedule Your Comprehensive Consultation
Call Today: (602) 603-2458
Visit Our Valley Bariatric Locations
Gilbert Office
726 N. Greenfield Rd. Bldg. 2, Ste. 105
Gilbert, AZ 85234
Chandler Office
60 N. McClintock Dr. Ste. 2
Chandler, AZ 85226
Phone: (602) 603-2458
Fax: (602) 603-2469
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References
Clinical Trial Sources:
- STEP Trials (Semaglutide): Wilding JPH, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989-1002. The 14.9% mean weight loss with semaglutide group is substantially greater than the weight loss of 4.0 to 10.9% from baseline with approved antiobesity medications.
- SURMOUNT Trials (Tirzepatide): Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216. The majority (89% to 91%) of participants receiving 10-mg or 15-mg doses of tirzepatide achieved [5% or greater weight loss]. Weight reductions of 10% or more, 15% or more, and 20% or more… The majority of participants reached these three higher weight-loss targets (78–84%, 67–71%, and 50–57%, respectively).
- STEP Extension Study: Wilding JPH, et al. Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. Diabetes Obes Metab. 2022;24(8):1553-1564.
- SURMOUNT-3 Trial: Wadden TA, et al. Tirzepatide after intensive lifestyle intervention in adults with overweight or obesity: the SURMOUNT-3 phase 3 trial. Nat Med. 2023;29(11):2909-2918.
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Dr. Maria R. Brown is a board-certified general surgeon with fellowship training in bariatric and metabolic surgery, maintaining a 4.9-star Google rating as the highest-rated bariatric surgeon in the Phoenix market. Valley Bariatric combines the latest advances in medical and surgical weight loss with compassionate, individualized care designed for real people with busy lives.
Medical Disclaimer: This information is for educational purposes only and does not constitute medical advice. Individual results may vary. Always consult with a qualified healthcare provider before starting any weight loss medication or treatment program.
